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Help transform medical research.

Take Action to Transform Medical Research

Actions You Can Take:

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Show Your Support for Transforming Medical Research

What: Endorse PZI’s call to transform medical research

How: Sign on here!

Why: To show decision makers that there is a groundswell of support for medical and scientific research that protects and benefits people and animals

PZI is working to transform medical research to advance the ethics and science of medical research for the benefit of people and animals.

Each year, millions of animals—including dogs, cats, and monkeys—are used and killed in US laboratories. They’re forced to undergo painful experiments and to witness the pain and suffering of other animals.

In laboratories, animals must live with constant fear and pain, and they develop mental disorders, including severe depression and anxiety. They are deprived of the richness of life. Most animals don’t survive.

A growing number of doctors, scientists, and policy makers question the validity and reliability of animal experiments, including the risks such poor science poses to vulnerable human patients and populations.

Fortunately, there are more ethical, human-relevant research tools and methods that can be used to study diseases and potential lifesaving therapies.

Transforming medical research will lead to

  1. A more ethical and just research paradigm.
  2. Federal funding shifts.
  3. Improved standards in academic research and publication standards.
  4. More innovative and ethical education, training, and career pathways and pipelines.
  5. A coordinated and strategic roadmap toward more modernization and innovation that protects and benefits people and animals.
Bodhi, a coonhound, was used in animal research before he found a kind and loving home outside the laboratory.

Tell Congress: Support the FDA Modernization Act


What: Urge your US Representative to Pass the FDA Modernization Act

How: Contact them here!

Why: To eliminate the FDA’s outdated animal testing requirement for drug developers and promote more modern, ethical methods that benefit and protect people and animals

9/29/22 UPDATE: The US Senate passed the FDA Modernization Act by unanimous consent! Now we need you to urge your representative to do the same, so that we can get this bill passed and make history!

It’s time for FDA requirements to keep pace with scientific advances. Rather than require outdated animal testing, the FDA needs to allow drug developers to use the most modern, reliable, and human-relevant testing methods available.

The FDA Modernization Act 2.0 (S. 5002) would replace the FDA’s 80-year-old animal testing requirement and open the door to modern, ethical methods that protect humans and animals.

It would allow drug manufacturers to test the safety and effectiveness of new drugs by using the most modern methods including cell-based assays, organ chips, microphysiological systems, sophisticated computer modeling, and other human biology-based test methods.

Let your elected officials know that you want them to act on this bill. 

Read PZI CEO Dr. Hope Ferdowsian’s testimony to the Subcommittee on Health, Committee on Energy and Commerce in support of the FDA Modernization Act.

Dr. Charu Chandrasekera founded the Canadian Center for Alternatives to Animal Methods, which works to replace the use of animals in research.
Dr. Charu Chandrasekera founded the Canadian Center for Alternatives to Animal Methods, which works to modernize research.

Tell Congress: Support the Humane Research and Testing Act of 2021


What: Urge your US Senators and Representative to Cosponsor and Support the Humane Research and Testing Act of 2021 (HR 1744)

How: Contact them here!

Why: To prioritize promoting and funding non-animal methods within the National Institutes of Health

Many doctors, scientists and policymakers question the validity and reliability of applying knowledge gained from animal experiments to human ailments. Fortunately, we have a rapidly expanding array of modern, non-animal testing methods that provide reliable, human-relevant research results. 

The Humane Research and Testing Act of 2021 (HR 1744) would establish the National Center for Alternatives to Animal Research and Testing.

Working within the National Institutes of Health, the Center would be tasked with promoting and funding non-animal methods, as well as providing training and preferential funding to help researchers transition to  more human-relevant testing methods.

The Center would also require federally-funded researchers to develop plans to modernize research. This bill would lend much-needed accountability and transparency to federally-funded research.

Let your elected officials know that you want them to act on this bill. It just takes two easy steps:

  1. Go to the action page and enter your name and address below the message that will be sent to your federal legislator.
  2. Click the “Send Email” button, and the website will use your address to send your message directly to your Member of Congress. (You also have the option to make a phone call, and if you click on the “Make Phone Call” button, the website will provide you with the correct phone number to use.)

Watch this short video about this ground-breaking bill, developed by CAARE to enable the shift toward superior research methods.

Watch the Recording for the January 2022 Transforming Medical Research Event

It’s time to transform medical research.

The medical and scientific communities have made important advancements in human research ethics, and it’s time to make similar progress for animals.

On Thursday, January 27, 2022, Phoenix Zones Initiative hosted a virtual panel discussion with eight expert panelists who discussed how human research protections offer a framework toward a transformative research agenda that benefits and protects humans and animals.

Panelists explored how human research protections, including the principles and applications described in The Belmont Report, could be extended to protect animals used in research in the US each year, while accelerating advances in more ethical, human-centered research technology.

“Extending the Belmont Report principles to animals would…help promote increased transparency, improved academic standards of publishing and greater investments in more reliable and translatable human-centered, modern research methods. It might also have the benefit of recruiting younger and more diverse learners who care deeply about justice to participate in scientific innovation.”

~ Hope Ferdowsian, MD, MPH, CEO, Phoenix Zones Initiative, and
Associate Professor of Medicine, University of New Mexico School of Medicine

Use and share our teaching guide, to use with the event video. The guide includes important questions to spark discussion and critical thinking with undergraduate and graduate students.

See our Press Kit, which includes more information about the event, as well as an FAQ about transforming medical research, a backgrounder about medical research, and more about our expert panelists.

Thank you to our generous funders!

We’re grateful for the generosity of these funders, whose support fuels our efforts to transform medical research:

Carroll Petrie Foundation

Horne Family Foundation

LUSH Charity Pot

Watch and share our video about why we need a Belmont Report for Animals:

“I admire the fact that PZI’s vision is based on principles of social justice applied to all vulnerable beings, including animals held in and experimented on by the biomedical industry. Thanks to PZI’s global leadership, we can map out ways to work effectively for a world in which human health advances come from the most highly effective and ethical methods, those which are non-animal-based.”

~ Barbara J. King, PhD, author and Emerita Professor of Anthropology at William & Mary

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